:::Welcome to Trimedis:::

	CardioDetect™lab h-FABP
	CardioDetect™combi
	CardioDetect™quant

A high precision instrument for rapid quantification.

	High precision due to its advanced confocal LED detector technology.
	Stand-alone device with an intuitive and fast user interface.
	Option to control the reader via a computer allowing even more convenient handling, data storage and printing.
	Rechargeable batteries allowing mobile use for several hours.
	Simple installation of calibration curves updates for new batches of CardioDetect, assuring batch to batch consistency.

h-FABP The new biomarker

Human h-FABP (heart-type fatty acid binding protein) is a low molecular cytoplasmic protein (14.9 kDa). It is present extensively in the myocardium. The skeletal muscles also contain h-FABP, but the concentration is several fold lower. Thus, h-FABP is highly specific for the myocardium. In healthy individuals the reference value of h-FABP is relatively low (2-5 ng/ml). Immediately after the onset of myocardial ischemia h-FABP is released into the bloodstream. Within 24 hours it is washed out by renal clearance.

The traditional markers like Troponin and CK-MB are elevated not before hours after the infarction. In contrast h-FABP can be detected very soon after the infarction.

The diagnostic reliabity of h-FABP for the early detection of AMI has been tested in a number of clinical studies. In these studies h-FABP showed a significantly higher sensitivity than Troponin while the specificity was slightly lower. The overall diagnostic efficacy was significantly higher for h-FABP.